In his quest for perfect realization and enlightenment, the Buddha first realized the imperfections of life.
The four signs of birth, old age, sickness and death left a deep and profound meaning to what life meant and he sought for answers to which he later discovered with his own effort.
Likewise, in order to perfectly understand the Dharma which is beautiful in the beginning, middle and end, we need to understand the nature of imperfections.
The more we seek for perfection, the more it becomes inevitable that we will soon realize the importance of imperfections.
Thus is revealed the true nature of all living beings which are suffering (dukkha), impermanence (anicca) and non-self (anatta).
To live in existence is to live in a constant flux of change.